Sha Cao Selected Research

apramycin

10/2022	Translational in vitro and in vivo PKPD modelling for apramycin against Gram-negative lung pathogens to facilitate prediction of human efficacious dose in pneumonia.
11/2021	Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.
9/2021	Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice.
1/2019	In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii.

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Sha Cao Research Topics

Disease

17	Neoplasms (Cancer) 10/2023 - 05/2015
6	Breast Neoplasms (Breast Cancer) 10/2023 - 05/2015
6	Infections 10/2022 - 01/2017
6	Anthrax 11/2012 - 05/2008
2	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 04/2023
2	Cognitive Dysfunction 12/2023 - 04/2023
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 01/2021
2	Inflammation (Inflammations) 01/2022 - 05/2015
2	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2015
2	Urinary Tract Infections (Urinary Tract Infection) 11/2021 - 01/2020
2	Edema (Dropsy) 11/2012 - 06/2010
1	Sepsis (Septicemia) 04/2024
1	Triple Negative Breast Neoplasms 08/2023
1	Starvation 04/2023
1	Hemophilia A (Haemophilia) 01/2023
1	Fatty Liver 01/2023
1	Fibrosis (Cirrhosis) 01/2023
1	Non-alcoholic Fatty Liver Disease 01/2023
1	Hemorrhage 01/2023
1	Pneumonia (Pneumonitis) 10/2022
1	Noninfiltrating Intraductal Carcinoma (DCIS) 08/2022
1	Disease Progression 01/2022
1	Pyelonephritis 11/2021
1	Atrophy 01/2021
1	Cachexia 01/2021
1	Pyuria 01/2020
1	Colorectal Neoplasms (Colorectal Cancer) 01/2020
1	Carcinogenesis 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020
1	Heart Failure 01/2019
1	Aneuploidy (Aneuploid) 01/2019
1	Trisomy 13 Syndrome 01/2019
1	Hemolysis 09/2018

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2010
5	Anti-Bacterial Agents (Antibiotics)IBA 11/2021 - 07/2011
4	AntigensIBA 01/2023 - 06/2010
4	apramycinIBA 10/2022 - 01/2019
4	Adenosine Triphosphate (ATP)IBA 01/2019 - 05/2015
3	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2020
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2023 - 06/2015
3	AminoglycosidesIBA 11/2021 - 01/2017
3	NucleotidesIBA 10/2018 - 01/2017
2	Amyloid (Amyloid Fibrils)IBA 12/2023 - 04/2023
2	AsparagineIBA 04/2023 - 11/2017
2	Glutamic Acid (Glutamate)FDA Link 01/2023 - 11/2017
2	EnzymesIBA 01/2023 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 05/2015
2	Glutamine (L-Glutamine)FDA Link 01/2023 - 11/2017
2	Glutathione (Reduced Glutathione)IBA 01/2023 - 01/2017
2	Carbapenems (Carbapenem Antibiotics)IBA 10/2022 - 09/2021
2	Indicators and Reagents (Reagents)IBA 08/2022 - 11/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 07/2015
2	anthrax toxin (anthrax lethal factor)IBA 11/2012 - 06/2010
2	VaccinesIBA 11/2010 - 10/2009
2	Metalloproteases (Metalloproteinases)IBA 11/2010 - 05/2008
2	AntitoxinsIBA 11/2010 - 06/2010
1	Blood Proteins (Serum Proteins)IBA 04/2024
1	Transcription Factors (Transcription Factor)IBA 10/2023
1	Epidermal Growth Factor (EGF)IBA 08/2023
1	ParaffinIBA 08/2023
1	Hormones (Hormone)IBA 08/2023
1	Formaldehyde (Formol)FDA Link 08/2023
1	Membrane Proteins (Integral Membrane Proteins)IBA 08/2023
1	IronIBA 04/2023
1	Histones (Histone)IBA 04/2023
1	Transferrin Receptors (Transferrin Receptor)IBA 04/2023
1	Nucleic AcidsIBA 01/2023
1	Amino Acids FDA Link 01/2023
1	MicroRNAs (MicroRNA)IBA 01/2023
1	CarbonIBA 01/2023
1	nasIBA 01/2023
1	Tricarboxylic AcidsIBA 01/2023
1	Messenger RNA (mRNA)IBA 01/2023
1	Cytochrome P-450 CYP2C19IBA 01/2023
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Amikacin (A.M.K)FDA LinkGeneric 11/2021
1	Gentamicins (Gentamicin)FDA LinkGeneric 11/2021
1	AminesIBA 11/2021
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2021
1	LipidsIBA 01/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021
1	PalmitatesIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	Protein CIBA 01/2020
1	cathepsin SIBA 01/2020
1	ChromatinIBA 01/2020
1	ChemokinesIBA 01/2020
1	leukocyte esteraseIBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 01/2020
1	transgelinIBA 01/2020
1	dichlorobis(azomycin)platinum IIIBA 01/2019
1	AcidsIBA 01/2019
1	EstersIBA 09/2018

Therapy/Procedure

9	Therapeutics 10/2023 - 06/2010
3	Immunotherapy 01/2024 - 01/2021
1	Precision Medicine 01/2023
1	Polypharmacy 01/2023
1	Lasers (Laser) 01/2020